L25I (p.Leu25Ile) variant of KRT6B (Keratin, type II cytoskeletal 6B)
L25I (p.Leu25Ile) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
L25I (p.Leu25Ile) variant details
- p.Leu25Ile
- ExAC rs759087767
- TOPMed rs759087767
- gnomAD rs759087767
- Missense
- Variant Prioritization Score for Impact Estimate 0.149
- REVEL 0.13
- CADD 3.23
- PolyPhen-2 0.00
- SIFT 0.48
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available