L118F (p.Leu118Phe) variant of KRT6B (Keratin, type II cytoskeletal 6B)
L118F (p.Leu118Phe) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
L118F (p.Leu118Phe) variant details
- p.Leu118Phe
- gnomAD rs1352637124
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.15
- CADD 10.30
- PolyPhen-2 0.00
- SIFT 0.71
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available