G89D (p.Gly89Asp) variant of KRT6B (Keratin, type II cytoskeletal 6B)
G89D (p.Gly89Asp) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
G89D (p.Gly89Asp) variant details
- p.Gly89Asp
- gnomAD rs1194903302
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.22
- CADD 18.30
- PolyPhen-2 0.23
- SIFT 0.02
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available