G81S (p.Gly81Ser) variant of KRT6B (Keratin, type II cytoskeletal 6B)
G81S (p.Gly81Ser) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G81S (p.Gly81Ser) variant details
- p.Gly81Ser
- Ensembl rs1448552830
- Missense
- Variant Prioritization Score for Impact Estimate 0.35
- REVEL 0.21
- CADD 10.80
- PolyPhen-2 0.01
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available