G66V (p.Gly66Val) variant of KRT6B (Keratin, type II cytoskeletal 6B)
G66V (p.Gly66Val) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
G66V (p.Gly66Val) variant details
- p.Gly66Val
- 1000Genomes rs562648897
- ExAC rs562648897
- TOPMed rs562648897
- gnomAD rs562648897
- Missense
- Variant Prioritization Score for Impact Estimate 0.368
- REVEL 0.36
- CADD 19.70
- PolyPhen-2 0.16
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available