G65R (p.Gly65Arg) variant of KRT6B (Keratin, type II cytoskeletal 6B)
G65R (p.Gly65Arg) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
G65R (p.Gly65Arg) variant details
- p.Gly65Arg
- NCI-TCGA TCGA novel
- Ensembl rs1940410762
- Variant assessed as somatic; high impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.542
- REVEL 0.62
- CADD 24.00
- PolyPhen-2 1.00
- SIFT 0.04
- UniProt: Variant assessed as somatic; high impact.
- Population evidence available
- Structural context available