G65E (p.Gly65Glu) variant of KRT6B (Keratin, type II cytoskeletal 6B)
G65E (p.Gly65Glu) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
G65E (p.Gly65Glu) variant details
- p.Gly65Glu
- ExAC rs779449161
- gnomAD rs779449161
- Missense
- Variant Prioritization Score for Impact Estimate 0.569
- REVEL 0.67
- CADD 23.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available