G63S (p.Gly63Ser) variant of KRT6B (Keratin, type II cytoskeletal 6B)
G63S (p.Gly63Ser) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
G63S (p.Gly63Ser) variant details
- p.Gly63Ser
- TOPMed rs1940410961
- Missense
- Variant Prioritization Score for Impact Estimate 0.092
- REVEL 0.11
- CADD 0.91
- PolyPhen-2 0.03
- SIFT 0.37
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available