A87D (p.Ala87Asp) variant of KRT6B (Keratin, type II cytoskeletal 6B)
A87D (p.Ala87Asp) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A87D (p.Ala87Asp) variant details
- p.Ala87Asp
- TOPMed rs1940409274
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.21
- CADD 9.63
- PolyPhen-2 0.01
- SIFT 0.04
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available