R86T (p.Arg86Thr) variant of KRT6A (Keratin, type II cytoskeletal 6A)
R86T (p.Arg86Thr) in KRT6A (Keratin, type II cytoskeletal 6A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
R86T (p.Arg86Thr) variant details
- p.Arg86Thr
- gnomAD rs1345402703
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.09
- CADD 21.90
- PolyPhen-2 0.15
- SIFT 0.12
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available