P26R (p.Pro26Arg) variant of KRT6A (Keratin, type II cytoskeletal 6A)
P26R (p.Pro26Arg) in KRT6A (Keratin, type II cytoskeletal 6A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
P26R (p.Pro26Arg) variant details
- p.Pro26Arg
- gnomAD rs1289441451
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- REVEL 0.34
- CADD 23.10
- PolyPhen-2 0.17
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available