K68R (p.Lys68Arg) variant of KRT6A (Keratin, type II cytoskeletal 6A)
K68R (p.Lys68Arg) in KRT6A (Keratin, type II cytoskeletal 6A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
K68R (p.Lys68Arg) variant details
- p.Lys68Arg
- gnomAD rs1487839397
- Missense
- Variant Prioritization Score for Impact Estimate 0.125
- REVEL 0.09
- CADD 15.70
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available