I108T (p.Ile108Thr) variant of KRT6A (Keratin, type II cytoskeletal 6A)
I108T (p.Ile108Thr) in KRT6A (Keratin, type II cytoskeletal 6A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
I108T (p.Ile108Thr) variant details
- p.Ile108Thr
- gnomAD rs1317216341
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.24
- CADD 2.09
- PolyPhen-2 0.00
- SIFT 0.42
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available