G74A (p.Gly74Ala) variant of KRT6A (Keratin, type II cytoskeletal 6A)
G74A (p.Gly74Ala) in KRT6A (Keratin, type II cytoskeletal 6A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
G74A (p.Gly74Ala) variant details
- p.Gly74Ala
- TOPMed rs1449780449
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.37
- CADD 15.20
- PolyPhen-2 0.01
- SIFT 0.12
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available