G66V (p.Gly66Val) variant of KRT6A (Keratin, type II cytoskeletal 6A)
G66V (p.Gly66Val) in KRT6A (Keratin, type II cytoskeletal 6A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G66V (p.Gly66Val) variant details
- p.Gly66Val
- TOPMed rs928566529
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.31
- CADD 22.70
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available