G65R (p.Gly65Arg) variant of KRT6A (Keratin, type II cytoskeletal 6A)
G65R (p.Gly65Arg) in KRT6A (Keratin, type II cytoskeletal 6A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
G65R (p.Gly65Arg) variant details
- p.Gly65Arg
- TOPMed rs1376405967
- gnomAD rs1376405967
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- REVEL 0.45
- CADD 23.50
- PolyPhen-2 0.94
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available