G17S (p.Gly17Ser) variant of KRT6A (Keratin, type II cytoskeletal 6A)
G17S (p.Gly17Ser) in KRT6A (Keratin, type II cytoskeletal 6A) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
G17S (p.Gly17Ser) variant details
- p.Gly17Ser
- NCI-TCGA Cosmic COSV5810
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.09
- CADD 9.79
- PolyPhen-2 0.12
- SIFT 0.16
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available