A23P (p.Ala23Pro) variant of KRT6A (Keratin, type II cytoskeletal 6A)
A23P (p.Ala23Pro) in KRT6A (Keratin, type II cytoskeletal 6A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
A23P (p.Ala23Pro) variant details
- p.Ala23Pro
- Ensembl rs1406917541
- Missense
- Variant Prioritization Score for Impact Estimate 0.524
- REVEL 0.52
- CADD 24.70
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available