A106T (p.Ala106Thr) variant of KRT6A (Keratin, type II cytoskeletal 6A)
A106T (p.Ala106Thr) in KRT6A (Keratin, type II cytoskeletal 6A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
A106T (p.Ala106Thr) variant details
- p.Ala106Thr
- TOPMed rs1187060006
- gnomAD rs1187060006
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.04
- CADD 13.40
- PolyPhen-2 0.06
- SIFT 0.21
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available