A106G (p.Ala106Gly) variant of KRT6A (Keratin, type II cytoskeletal 6A)
A106G (p.Ala106Gly) in KRT6A (Keratin, type II cytoskeletal 6A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
A106G (p.Ala106Gly) variant details
- p.Ala106Gly
- TOPMed rs1440511992
- gnomAD rs1440511992
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.04
- CADD 8.41
- PolyPhen-2 0.00
- SIFT 0.78
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available