S36Y (p.Ser36Tyr) variant of KRT5 (Keratin, type II cytoskeletal 5)
S36Y (p.Ser36Tyr) in KRT5 (Keratin, type II cytoskeletal 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
S36Y (p.Ser36Tyr) variant details
- p.Ser36Tyr
- gnomAD rs1938693726
- Missense
- Variant Prioritization Score for Impact Estimate 0.454
- REVEL 0.40
- CADD 24.40
- PolyPhen-2 0.42
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available