R73T (p.Arg73Thr) variant of KRT5 (Keratin, type II cytoskeletal 5)
R73T (p.Arg73Thr) in KRT5 (Keratin, type II cytoskeletal 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
R73T (p.Arg73Thr) variant details
- p.Arg73Thr
- TOPMed rs1285526841
- gnomAD rs1285526841
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.18
- CADD 21.30
- PolyPhen-2 0.02
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available