I74T (p.Ile74Thr) variant of KRT5 (Keratin, type II cytoskeletal 5)
I74T (p.Ile74Thr) in KRT5 (Keratin, type II cytoskeletal 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
I74T (p.Ile74Thr) variant details
- p.Ile74Thr
- TOPMed rs1463063008
- gnomAD rs1463063008
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.20
- CADD 21.40
- PolyPhen-2 0.00
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available