I23T (p.Ile23Thr) variant of KRT5 (Keratin, type II cytoskeletal 5)
I23T (p.Ile23Thr) in KRT5 (Keratin, type II cytoskeletal 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
I23T (p.Ile23Thr) variant details
- p.Ile23Thr
- Ensembl rs1809920681
- Missense
- Variant Prioritization Score for Impact Estimate 0.35
- REVEL 0.21
- CADD 20.60
- PolyPhen-2 0.02
- SIFT 0.72
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available