G92R (p.Gly92Arg) variant of KRT5 (Keratin, type II cytoskeletal 5)
G92R (p.Gly92Arg) in KRT5 (Keratin, type II cytoskeletal 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
G92R (p.Gly92Arg) variant details
- p.Gly92Arg
- TOPMed rs1428870322
- gnomAD rs1428870322
- Missense
- Variant Prioritization Score for Impact Estimate 0.451
- REVEL 0.30
- CADD 22.60
- PolyPhen-2 0.01
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available