G81S (p.Gly81Ser) variant of KRT5 (Keratin, type II cytoskeletal 5)
G81S (p.Gly81Ser) in KRT5 (Keratin, type II cytoskeletal 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G81S (p.Gly81Ser) variant details
- p.Gly81Ser
- gnomAD rs1938689437
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.05
- CADD 14.20
- PolyPhen-2 0.01
- SIFT 0.36
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available