F87S (p.Phe87Ser) variant of KRT5 (Keratin, type II cytoskeletal 5)
F87S (p.Phe87Ser) in KRT5 (Keratin, type II cytoskeletal 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
F87S (p.Phe87Ser) variant details
- p.Phe87Ser
- ESP rs375333850
- ExAC rs375333850
- TOPMed rs375333850
- gnomAD rs375333850
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.03
- CADD 14.60
- PolyPhen-2 0.01
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available