V33I (p.Val33Ile) variant of KRT4 (Keratin, type II cytoskeletal 4)
V33I (p.Val33Ile) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
V33I (p.Val33Ile) variant details
- p.Val33Ile
- ESP rs376868011
- ExAC rs376868011
- TOPMed rs376868011
- gnomAD rs376868011
- Missense
- Variant Prioritization Score for Impact Estimate 0.0793
- REVEL 0.07
- CADD 0.58
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available