V33F (p.Val33Phe) variant of KRT4 (Keratin, type II cytoskeletal 4)
V33F (p.Val33Phe) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
V33F (p.Val33Phe) variant details
- p.Val33Phe
- ESP rs376868011
- ExAC rs376868011
- TOPMed rs376868011
- gnomAD rs376868011
- Missense
- Variant Prioritization Score for Impact Estimate 0.0745
- REVEL 0.06
- CADD 1.37
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available