S64C (p.Ser64Cys) variant of KRT4 (Keratin, type II cytoskeletal 4)
S64C (p.Ser64Cys) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S64C (p.Ser64Cys) variant details
- p.Ser64Cys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.30
- CADD 22.30
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available