N58K (p.Asn58Lys) variant of KRT4 (Keratin, type II cytoskeletal 4)
N58K (p.Asn58Lys) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
N58K (p.Asn58Lys) variant details
- p.Asn58Lys
- TOPMed rs905272775
- gnomAD rs905272775
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.11
- CADD 4.99
- PolyPhen-2 0.03
- SIFT 0.10
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available