M35T (p.Met35Thr) variant of KRT4 (Keratin, type II cytoskeletal 4)
M35T (p.Met35Thr) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
M35T (p.Met35Thr) variant details
- p.Met35Thr
- ExAC rs748899502
- gnomAD rs748899502
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.15
- CADD 13.30
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available