K59E (p.Lys59Glu) variant of KRT4 (Keratin, type II cytoskeletal 4)
K59E (p.Lys59Glu) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
K59E (p.Lys59Glu) variant details
- p.Lys59Glu
- gnomAD rs982339709
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.34
- CADD 21.60
- PolyPhen-2 0.05
- SIFT 0.00
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available