I61T (p.Ile61Thr) variant of KRT4 (Keratin, type II cytoskeletal 4)
I61T (p.Ile61Thr) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
I61T (p.Ile61Thr) variant details
- p.Ile61Thr
- TOPMed rs1939959799
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.11
- CADD 14.30
- PolyPhen-2 0.00
- SIFT 0.07
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available