G91V (p.Gly91Val) variant of KRT4 (Keratin, type II cytoskeletal 4)
G91V (p.Gly91Val) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
G91V (p.Gly91Val) variant details
- p.Gly91Val
- ExAC rs773161343
- gnomAD rs773161343
- Missense
- Variant Prioritization Score for Impact Estimate 0.595
- REVEL 0.48
- CADD 23.40
- PolyPhen-2 0.58
- SIFT 0.03
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available