G90W (p.Gly90Trp) variant of KRT4 (Keratin, type II cytoskeletal 4)
G90W (p.Gly90Trp) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
G90W (p.Gly90Trp) variant details
- p.Gly90Trp
- ExAC rs760542950
- TOPMed rs760542950
- gnomAD rs760542950
- Missense
- Variant Prioritization Score for Impact Estimate 0.573
- REVEL 0.49
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available