G90V (p.Gly90Val) variant of KRT4 (Keratin, type II cytoskeletal 4)
G90V (p.Gly90Val) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
G90V (p.Gly90Val) variant details
- p.Gly90Val
- Ensembl rs1939955492
- Missense
- Variant Prioritization Score for Impact Estimate 0.667
- REVEL 0.60
- CADD 23.40
- PolyPhen-2 0.98
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available