G76V (p.Gly76Val) variant of KRT4 (Keratin, type II cytoskeletal 4)
G76V (p.Gly76Val) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G76V (p.Gly76Val) variant details
- p.Gly76Val
- ExAC rs753941027
- gnomAD rs753941027
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.09
- CADD 11.20
- PolyPhen-2 0.08
- SIFT 0.12
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available