G107R (p.Gly107Arg) variant of KRT4 (Keratin, type II cytoskeletal 4)
G107R (p.Gly107Arg) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
G107R (p.Gly107Arg) variant details
- p.Gly107Arg
- NCI-TCGA Cosmic COSV9954
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.679
- REVEL 0.58
- CADD 26.40
- PolyPhen-2 1.00
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available