F101L (p.Phe101Leu) variant of KRT4 (Keratin, type II cytoskeletal 4)
F101L (p.Phe101Leu) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
F101L (p.Phe101Leu) variant details
- p.Phe101Leu
- TOPMed rs1009740435
- gnomAD rs1009740435
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.39
- CADD 15.40
- PolyPhen-2 0.09
- SIFT 0.40
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available