A77T (p.Ala77Thr) variant of KRT4 (Keratin, type II cytoskeletal 4)
A77T (p.Ala77Thr) in KRT4 (Keratin, type II cytoskeletal 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
A77T (p.Ala77Thr) variant details
- p.Ala77Thr
- ExAC rs756562144
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.33
- CADD 16.80
- PolyPhen-2 0.01
- SIFT 0.16
- Population evidence available
- Structural context available