V32L (p.Val32Leu) variant of KRT3 (Keratin, type II cytoskeletal 3)
V32L (p.Val32Leu) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
V32L (p.Val32Leu) variant details
- p.Val32Leu
- ExAC rs747935399
- gnomAD rs747935399
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.24
- CADD 4.36
- PolyPhen-2 0.15
- SIFT 0.20
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available