V32E (p.Val32Glu) variant of KRT3 (Keratin, type II cytoskeletal 3)
V32E (p.Val32Glu) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
V32E (p.Val32Glu) variant details
- p.Val32Glu
- ExAC rs779168086
- gnomAD rs779168086
- Missense
- Variant Prioritization Score for Impact Estimate 0.413
- REVEL 0.51
- CADD 20.20
- PolyPhen-2 0.80
- SIFT 0.05
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available