S99R (p.Ser99Arg) variant of KRT3 (Keratin, type II cytoskeletal 3)
S99R (p.Ser99Arg) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
S99R (p.Ser99Arg) variant details
- p.Ser99Arg
- 1000Genomes rs148001170
- ExAC rs148001170
- TOPMed rs148001170
- gnomAD rs148001170
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- REVEL 0.21
- CADD 0.04
- PolyPhen-2 0.01
- SIFT 0.40
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available