S85R (p.Ser85Arg) variant of KRT3 (Keratin, type II cytoskeletal 3)
S85R (p.Ser85Arg) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
S85R (p.Ser85Arg) variant details
- p.Ser85Arg
- ExAC rs778394515
- TOPMed rs778394515
- gnomAD rs778394515
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.13
- CADD 7.50
- PolyPhen-2 0.00
- SIFT 0.22
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available