S67T (p.Ser67Thr) variant of KRT3 (Keratin, type II cytoskeletal 3)
S67T (p.Ser67Thr) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
S67T (p.Ser67Thr) variant details
- p.Ser67Thr
- TOPMed rs1939633323
- gnomAD rs1939633323
- Missense
- Variant Prioritization Score for Impact Estimate 0.387
- REVEL 0.42
- CADD 22.30
- PolyPhen-2 0.32
- SIFT 0.01
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available