I66F (p.Ile66Phe) variant of KRT3 (Keratin, type II cytoskeletal 3)
I66F (p.Ile66Phe) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
I66F (p.Ile66Phe) variant details
- p.Ile66Phe
- 1000Genomes rs2121226557
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.48
- CADD 23.60
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available