H34R (p.His34Arg) variant of KRT3 (Keratin, type II cytoskeletal 3)
H34R (p.His34Arg) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
H34R (p.His34Arg) variant details
- p.His34Arg
- gnomAD rs1437272363
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.17
- CADD 1.14
- PolyPhen-2 0.00
- SIFT 0.47
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available