G91S (p.Gly91Ser) variant of KRT3 (Keratin, type II cytoskeletal 3)
G91S (p.Gly91Ser) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G91S (p.Gly91Ser) variant details
- p.Gly91Ser
- NCI-TCGA Cosmic COSV5881
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- REVEL 0.23
- CADD 11.90
- PolyPhen-2 0.00
- SIFT 0.11
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available