G81V (p.Gly81Val) variant of KRT3 (Keratin, type II cytoskeletal 3)
G81V (p.Gly81Val) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
G81V (p.Gly81Val) variant details
- p.Gly81Val
- 1000Genomes rs552886568
- ExAC rs552886568
- TOPMed rs552886568
- gnomAD rs552886568
- Missense
- Variant Prioritization Score for Impact Estimate 0.594
- REVEL 0.64
- CADD 22.10
- PolyPhen-2 0.98
- SIFT 0.04
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available